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Nervous System 2018

About Conference

Nervous System 2018 Organizing Committee, invites all the participants from all over the world to attend “International conference on Nervous System and Nerve Diseases” during September 17-18, 2018 at Philadelphia, USA. This gathering is predominantly will focus the most recent and energizing developments in each range of Nervous System research and it will offer an exceptional opportunity for specialists from all over the world to meet, network, and distinguish with different scientific interactions.

The nervous system is the part of our body that consists of two major parts namely Central Nervous System and Peripheral Nervous System. CNS consists of Brain and Spinal Cord and PNS consists of Ganglia and nerves outside the Brain and Spinal cord. The main function of CNS is to control the activities of the body and PNS is responsible for the connection between CNS and limbs and other organs in the body. The brain is shielded with skull bones and the spinal cord streams from the back of the brain, down the focal point of the spine in the spinal channel, halting in the lumbar region. The retina, optic nerve, olfactory nerves and olfactory epithelium are thought to be the part of Central nervous system.

Since PNS is not protected with skull or any column, it is often exposed to toxins and mechanical injuries. PNS is subdivided into somatic Nervous system and Autonomic Nervous System. Peripheral Neuropathy refers to the damage caused in the peripheral nerve that disrupts the passage of messages between CNS and PNS. The spinal cord and Brian are covered with the membrane called Meningitis.

There are about more than 100 different kinds of Nervous Disorders. The commonness of myasthenia gravis in the United States is assessed at 14 to 20 for each 100,000 populaces, around 36,000 to 60,000 cases in the United States. Notwithstanding, myasthenia gravis remains underdiagnosed and the predominance is most likely higher. Myasthenia Gravis is an autoimmune disease that occurs when there is disruption in transferring nerve signals to the muscles.

Approximately 20 million adults in USA are affected with diabetic Peripheral Neuropathy. About 86 million people with pre- diabetes are at risk of having Peripheral Neuropathy, from where 21.5 million were diagnosed with Peripheral Neuropathy. It is estimated that 20- 50% of HIV patients were suffering from Peripheral Neuropathy. 30% of cancer survivors were suffering from Chemotherapy induced Peripheral Neuropathy. The fact is that about half of the 42.5 million people don’t even know that they are affected with Neuropathy.

Why to attend?

Nervous System 2018 will provide an opportunity to world researchers working in era of neurological disorders to deliver talk on their research. It will be a great opportunity to the speakers, experts, researchers from both academics and industrialist to discuss their research and views.

It is our greatest pleasure to welcome you to the “International conference on Nervous System and Nerve Diseases” (Nervous System 2018), September 17-18, 2018 at Philadelphia, USA. The conference includes demonstration, symposium, workshops with different tracks in the field of neurological disorder. Nervous System 2018 is the leading gathering of neurologists, psychiatry, psychology researchers, and neurosurgeons with the theme of Research Strategies, propelled advancements and developments in Neuropathy. Its main aim to deliver and exchange ideas with the leading scientists and to create awareness among people about Neuropathy.

Target audience: Neurologists, Psychiatrists, Psychologists, Neurosurgeon, Head of the department, Director, Industries, Delegates, Clinical, Community members, Professors, Researchers, Students, Scientists, Nurses.

· Neurologists and Directors

· Physicians

· Neuroscientists

· Specialists

· Researchers

· Professors

· Industrial Experts

· Neurosurgeons

· Psychiatrist

· Nutritional Scientists

· Lecturers and Students from Academia in the study of Parkinson disease

· Students from Academia in the research of Neurology and Neuroscience

· Therapists

Target Audience

Industry 10%

Academia 50%

Clinicians 20%

Others 10%

University 10%

Sessions/ Tracks

Session on Nervous System

Nervous System comprises of Central Nervous System and Peripheral Nervous System. Nervous System consists of two types of cells namely neurons and glial cells. Neurons communicate with other cells through synapses which allow transmission of signals either electrical or chemical signals. Neurons possesses axons, a protoplasmic bulge that can stretch out to distant parts of the body and make a huge number of synaptic contacts. Axons much of the time go through the body in groups called nerves.Glial cells are non- neuronal cells, that offer support and nourishment, retain homeostasis, form myelin and involve in the signal transmission in the nervous system.

The Nervous System has three overlapping functions such as sensory input, intergration and motor output. At a more integrative level, the fundamental function of Nervous system is to control and communicate information all through the body

3^rd International Conference on Neurological Disorders and Stroke, Apr 24-25, 2017, Dubai, UAE; 12^th International Conference on Neurology and Neurophysiology May 18-20, 2017, Munich, Germany; 15th European Neurology Congress, Aug 29-31, 2017 London, UK; 18^th Global Neurologists Annual Meeting on Neurology and Neurosurgery, Nov 13-15 2017 Athens, Greece; 3^rd International Conference on Spine and Spinal Surgery, Oct 16-17, 2017 Chicago, USA; Neuroscience 2017, Nov 11-15, 2017, Washington, USA; Excitatory Synapses & Brain Function, May 28 - Jun 2, 2017, Switzerland; 4^th International Conference on Neurodegenerative disorders and Stroke, Jul 5-7, 2017, Frankfurt, Germany; American Association of Neuromuscular & Electrodiagnostic Medicine Annual Meeting, Sep 13-16, 2017, Arizona, USA; 11^th FENS Forum of Neuroscience, Jul 7-11, 2018, Berlin, Germany.

Session on Central Nervous System

Brachial Plexus is a connective Nerve that provides movements to shoulder, arm and hand which is in the neck region of the Spinal Cord. This nerve is composed of four cervical Nerve roots and the first thoracic nerve root. A birth Brachial Plexus injury is caused at the time delivery process. It was found to occur in 1.5 of every 1000 live births. Traumatic Brachial Plexus Injury is due to road accidents. Injuries are classified into four types namely Avulsion, Rupture, Neuroma, Neurapraxia. Surgery should be done to avulsion and rupture injuries. For Neuroma and Neuropraxia, the range of improvement varies. Many patients of Neuropraxia have gained 90-100% of their functions after the surgery.

14th Neurology and Neurological Disorders Congress, July 17-18, 2017, Chicago, USA; 17th Neuroscience Conference, October 16-17, 2017 Osaka, Japan; 9th International Conference on Alzheimer’s Disease & Dementia, 16-18 October 2017, Rome, Italy; 11th International Conference on Frontotemporal Dementia, November 11-14, 2018, Sydney, Australia; 10th Clinical Trials on Alzheimer's Disease (CTAD), 1-4 November 2017, Boston, MA, USA; 27th Alzheimer Europe Conference, 2-4 October 2017, Berlin, Germany; 11th International Conference on Vascular Dementia, 22-23 February 2018, Paris, France; 18th International Conference on Alzheimer’s Drug Discovery, 11-12 September 2017, Jersey City, NJ, USA; Alzheimer's Australia National Conference, 17–20 October 2017, Melbourne, Australia.

Session on ANS and PNS

Peripheral Nervous system contains Ganglia and Nerves outside the Brain and spinal cord. PNS often exposed to toxins and mechanical injuries since it is not protected by skull or vertebral column. PNS is partitioned into Somatic Nervous System and Autonomic Nervous System (ANS). The predominant function is to carry signals from Central Nervous System to all other organs of the body.

ANS controls certain body function such as blood pressure and heart rates without any conscious effort of the person. Two neurotransmitters used to interact within the autonomic nervous system are Acetylcholine and Norepinephrine. Other functions are body temperature, digestion, urination, defecation and production of body fluids.

3^rd International Conference on Neurological Disorders and Brain Injury, Apr 18- 19, 2017 London, UK; 2^ndInternational Conference on Neuro Oncology and Neurosurgery, Apr 24-25, 2017 Dubai, UAE; 5^th International Conference on Brain Disorders and Therapeutics, Nov 6-8, 2017 Madrid, Spain; 3^rd International Conference on Brain Disorders and Therapeutics Nov 06-08, 2017 Valencia, Spain; 20^th International Conference on Neuroscience and Neurochemistry, Feb 26-27, 2018 Berlin, Germany; 2^nd International Conference on Spine and Spinal Disorders, Jul 24-26, 2017, Rome, Italy; 15^th European Neurology Congress, Aug 29-31, 2017 London, UK; 3^rd International Conference on Spine and Spinal Surgery, Oct 16-17, 2017 Chicago, USA; 17^th Global Neuroscience Conference, Oct 16-17, 2017 Osaka, Japan;

Session on Brain and Spinal Cord injury

Spinal cord injury is the most devastating injury and over 17,000 Americans are affected by spinal cord injury each year. Around 5 lakhs people suffer spinal cord injury every year all over the world. 90% of the cases are due to traumatic causes. There are two stages in the treatments of Spinal Cord Injury namely Acute phase and rehabilitation phase.

Brain injury can be broadly classified into primary and secondary brain injury. There are two types of brain injuries: Traumatic brain injury and Diffuse axonal injury. In brain and spinal cord injuries, the transmission of impulses from Central nervous system to PNS is disrupted thereby affects the whole Nervous System.

Session on Stroke and Neurological Disorders

There are about 600 neurological disorders and approximately 50 million Americans are being affected each year. The main risk factors for neurological disorders are genetic manipulation, age, lifestyle and other environmental agents. Abnormalities in structural and biochemical functions causes various symptoms. Some of them are paralysis, seizures, confusion, muscle weakness and altered levels of consciousness.

Session on Neuropathy

Peripheral neuropathy is one of the nervous system disorders. Depending on the nerves it may repair sensation, movement and organ functions. The main causes of this disorder are viral infection, vitamin deficiency, immune system diseases and medication like chemotherapy or antibiotics. There are many types of nervous system disorder according to the number of nerves affected, type of nerve affected and the process of nerve damage.

Session on Neuropathic pain and Management

It is caused by damage or any dysfunction of nerve, spinal cord or brain. It may occur due to compression of a nerve or nerve damage. Neuropathic pain is also responsible for anxiety and depression which worsen the neuropathic pain. It is characterized by burning or tingling, or hypersensitivity to touch or cold. Treatments include physical therapy or occupational therapy, pain relievers or surgery, electrical stimulation or nerve blocks.

Session on Multiple Sclerosis

Multiple sclerosis is a disorder in which the myelin sheath that covers most of the nerve fibers is damaged or destroyed. The cause is unknown but it is an autoimmune disorder. This disorder is also called demyelination. Symptoms is based on the nerve fiber that are demyelinated. Moreover, the typical patterns of symptoms are Relapsing-remitting pattern, Primary progressive pattern, Secondary progressive pattern, Progressive relapsing pattern. If the sheath is able to repair nerve fibers, the normal function of nerve fibers can be recovered. Nonetheless, if the sheath is extremely damaged, the nerve fiber can be destroyed completely. The nerve fibers in CNS cannot be regenerated by themselves. Consequently, these nerve fibers are permanently damaged.

Session on Parkinson’s and Movement Disorders

Each body movement, from raising a hand to grinning, includes a complex connection between the Central Nervous system (mind and spinal cord), nerves, and muscles. Destruction of any of these segments may bring about a movement disorders. Depending on the nature and location damage or malfunction, different types of movement disorders can form such as damage to the part of brain that controls voluntary movements, damage to the basal ganglia or damage to cerebellum.

Session on Neuroplasticity

The ability of the Brain to alter at any age is referred to as Neuroplasticity or Brain Plasticity. The recent neuroscience research proves that Neuroplasticity is the basis for brain training exercises which revolutionized the brain health and science research. There is a great reception for Brain plasticity based therapies for many cognitive problems since it is a non- invasive treatment.

Session on Neuroregenaration

Regrowth of Nervous tissues and cells including Neurons, glia, axons, myelin or synapses is known as Neuroregenaration. On site of the injury in Peripheral Nervous System, the migration of phagocytes, Schwann cells and macrophages will be elicited to clear away the damages tissues. The regrowth of Axons can occur after injury. Neuroregenaration in Peripheral Nervous System happens to a certain degree.

Session on Diagnosis of Neuropathy

Identification of Peripheral Nerve disorder can be done in my ways. Mainly Nerve Conduction tests and Electromyography(EMG). Other tests include Autonomic testing, Cerebrospinal Fluid Analysis and Nerve Biopsy Analysis. The attention must be given to the types of nerves affected and the pattern of involvement. Diabetes is one of the main causes of Peripheral Nervous Disorder. Eventually Diabetes people have high risk for Peripheral Nerve injury.

7^th International Conference on Dementia and Care Practice, May 04-05, 2017, Toronto, Canada; 2^nd International Conference on Neuro Rehabilitation, May 25-26, 2017, Chicago , USA; 2^nd International Conference on Spine and Spinal Disorders, Jul 24-26, 2017, Rome, Italy; 3^rd International Conference on Neuro Infectious Disorders, Aug 28-30, 2017, Philadelphia, USA; 6^th World Pharmacists & Clinical Pharmacy Annual Congress, May 22-23, 2017 (10 Plenary Forums - 1 Event), Chicago, Illinois, USA; 14^th World Congress on Neurology and Neurological Disorders, Jul 17-18, 2017 Chicago, USA; 7^th Global Experts Meeting on Neuropharmacology, Jul 31-Aug 02, 2017, Milan, Italy; 15^th European Neurology Congress, Aug 29-31, 2017 London, UK; 16^th International Conference on Neurology and Neuro Cognitive Disorders, Oct 09-10, 2017 London, UK;

Session on Therapeutics Approaches to Neuropathy

Treatment for the Peripheral Nerve Disorder is based on the causes of disorder. Pain medications can be given to the patients for controlling moderate pain. Another potential therapy is Transcutaneous electronic nerve stimulation (TENS). This treatment helps in disrupting nerves from transmitting pain signals to the brain. Ergonomic casts or splints helps in relieving pain. Demyelinating Neurotherapies is fast growing technique to treat Peripheral Nerve Disorder.

Session on Neuroimaging

The tools used for imaging Peripheral Nerve are Positron Emission Tomography(PET), Diffusion Tensor imaging(DTI), Magnetic Resonance Neurography(MRN), Computerized Tomography(CT), Plain X- Ray. MRN is the advanced technique used to image Peripheral Nerve for the diagnosis of any disorder in the Nerves and Neuromuscular diseases. It can image any Nerves in the body and are commonly used for the diagnosis of Nerve disorder in Brachial Plexus.

2nd International Conference on Neuroimaging and Interventional Radiology, Oct 30 - Nov 01, 2017, SAN ANTONIO, USA; 3rd International Conference on Neuroradiology & Imaging, May 30-31, 2018, OSAKA, JAPAN. 17^th Global Neuroscience Conference, Oct 16-17, 2017 Osaka, Japan; 5^th Quadrennial Meeting of The World Federation of Neuro-Oncology Societies (WFNOS), May 4-7, 2017, Zurich, Switzerland; 5^th International CNS Germ Cell Tumor Symposium, Jun 7-10, 2017, Columbus, USA; Paediatric Neuro-Oncology Basic and Translational Research Conference, Jun 15-16, 2017, New York, USA; 2017 SNO Meeting, Nov 16 – 19, 2017, San Francisco, California, USA.

Market Analysis

Theme: Exploring Novelty and Vision on Nervous System and Nerve Disorders

On behalf of the Conference Organizing Committee, it is our heartiest welcome you to the "International Conference on Nervous System and Nerve Diseases" during September 17-18, 2018 in Philadelphia, USA.

Importance and Scope:

The nervous system is a complex system of nerves and cells that convey messages to and from the brain and spinal cord to different parts of the body. The Nervous system incorporates both the Central sensory system and Peripheral sensory system. The Central nervous system is comprised of the brain and spinal cord and the Peripheral nervous system is comprised of the Somatic and the Autonomic nervous systems.

The Nervous Disorders may involve:

Vascular disorders
Infections
Structural disorders
Functional disorders
Degeneration

Group of neurological disorders that affect the structure and function of brain and spinal cord is termed as Central Nervous System Disorders. Some of them are Addiction, Autism, Bipolar disorder, Depression, Encephalitis, Epilepsy/Seizures, Alzheimer’s, Parkinson's Disease.

Peripheral Nervous system disorder mainly causes due to damage occurred to peripheral nerves resulting in weakness, numbness, and usually in hands and feet. Peripheral Neuropathy is caused due to traumatic injuries, infections, metabolic problems, inherited causes and exposure to toxins, and most commonly by diabetes mellitus.

Electrodiagnostic studies are a critical early stride in the analytic assessment and give data on the confinement and pathophysiology of nerve damage.

Why Philadelphia?

Philadelphia is the largest city in the commonwealth of Pennsylvania and sixth most populous city in United states with the population of 1.5million as of 2016.

It is known for its arts, culture and rich history, attracting about 41million local tourists lone in 2015. This city is the birth place of United states firsts namely first library, first hospital and medical school, first Capital, first stock exchange, first zoo, and first business school.

The 67 National Historic Landmarks in the city helped account for the $10 billion generated by tourism. Philadelphia has become one of the top international study destination and emerged into an educational and economic hub.

Philadelphia's economic areas incorporate information innovation, oil refining, Food processing, human services, biotechnology, tourism, and budgetary administrations. Money related exercises represent the biggest segment of the metropolitan zone's economy, and it is one of the biggest wellbeing education and research centers in the United States.

This city is notable for its museums of art such as the Pennsylvania Academy of the Fine Arts and the Rodin Museum. Pennsylvania Museum of Art is the largest museum in the United States.

The U.S. Census Bureau stated that, the fastest growing segment of the U.S. population is geriatric group. In the base 2016, North America was observed as the largest market for peripheral neuropathy. The rising geriatric population, growing incidences of diabetes in the region is the prime factor driving the North America peripheral neuropathy market.

Market Value of PNS Globally

Geriatric and obese population is growing at a rapid pace across the world and these people are at high risk for developing peripheral neuropathy. Centers for Disease Control and Prevention stated, that people who are diagnosed with diabetes mostly obese. Thus, with rising geriatric population and growing prevalence of diabetes propels the global market demand of peripheral neuropathy treatment. According to World Health Organization (WHO) estimates, the global geriatric population would increase from 524 million in 2010 to around 2 billion by 2050. Moreover, the global geriatric population would grow at the fastest rate in developed countries such as the U.S., the U.K. and Japan. World Health Organization (WHO) stated in 2012 that, more than 40 million children under the age of 5 were overweight or obese. Moreover, it has also estimated that 10% of the world adult population was obese in the year 2012.

Market growth of PNS Globally

According to the latest market report the global peripheral neuropathy market was valued at US$ 1,470.9 million in 2016, and is expected to reach US$ 1,998.8 million by 2025, expanding at the rate of 3.2% from 2017 to 2025.

Peripheral Neuropathy market value in Europe

General population studies have reported that 7 to 8% adults currently have chronic neuropathic pain, where the reported incidence is of 8 cases per 1,000 individuals per year. In the U.K. alone, 26% individuals with diabetes experience peripheral neuropathic pain. Globally, this figure translates to approximately 50 million individuals, which will further increase as is anticipated that the prevalence of diabetes will grow to an estimated 4.4% by 2030.

Conference Highlights

Nervous System

Central Nervous system

ANS and PNS

Brain and Spinal Cord injury

Neurological Disorders

Neuropathy

Multiple Sclerosis

Neuropathic Pain

Parkinson's Diseases and Movement Disorders

Neuroplasticity

Neuroregenaration

Diagnosis of Nervous Disorders

Therapeutics of Nervous Disorders

Neuroimaging

Major Centers for Peripheral Neuropathy around the world

The Foundation for Peripheral Neuropathy

UCSF Medical Center

The Center for Peripheral Neuropathy

Emory Healthcare

Ohio State Neuromuscular Disorders

American Brain Foundation`

NYU Langone Medical Center

The National Organization for Rare Disorders (NORD)

List of Universities/ Colleges which are related to Nervous System

University of Chicago

University of Maryland Medical Center

Columbia University

University of Florida Health

University of Rochester

Ohio State University

New York University

Binghamton University

New York University

Binghamton University

University of Buffalo

Fordham University

Mount Saint Mary College

Hamilton College

Roberts Wesleyan College

Imperial College

List of Companies associated with Neuropathy:

Avanir pharmaceuticals

The Mount Desert Island (MDI) Biological Laboratory

Novo Biosciences

Astellas Pharmaceuticals

Depomed

AMRAD Pharmaceuticals

Immune Pharmaceuticals

TEVA Pharmaceutical Industries Ltd.

Eli Lilly

Endo International

Pfizer

Allodynic Therapeutics

Arbor Pharmaceuticals

Astellas Pharma

Biogen

CAPNIA

Centrexion Therapeutics

ContraVir Pharmaceuticals

Crescita Therapeutics

DAEWOONG

GlaxoSmithKline

Hydra Biosciences

Jiangsu Hengrui Medicine

Lexicon Pharmaceuticals

Mallinckrodt

Midatech Pharma

Neurotune

Newron Pharmaceuticals

Novaremed

Novartis

PledPharma

Premier Biomedical

Regeneron

Samyang Biopharmaceuticals

Sienna Biopharmaceuticals

TheraVasc

TORAY INDUSTRIES

Torrent Pharmaceuticals

UCB Pharma

VanWorld Pharmaceutical (a subsidiary of Vanway)

VistaGen Therapeutics

WEX Pharmaceuticals

WINSTON PHARMACEUTICALS

Yuhan Corporation

Products Used to treat Nerve Pain:

cyclooxygenase-2 inhibitors.

tramadol.

corticosteroid injections.

seizure medications, such as gabapentin or pregabalin.

antidepressants, such as amitriptyline.

Cymbalta, which is a serotonin norepinephrine reuptake inhibitor.

Important Dates

1st Lane of Abstract submission: October 20, 2017

2nd Lane of Abstract submission: November 20, 2017

3rd Lane of Abstract submission:December 20, 2017

Early Bird Discount Registration Offer: On/Before October 20, 2017

Past Conference Report

CNS 2016

Central Nervous System 2016- Reports

The 2nd International Conference on Central Nervous System Disorders and Therapeutics hosted by the Conference Series LLC was held on December 05-07, 2016 at JW Marriott Hotel, Dubai, UAE. Generous response and active participation was received from the Editorial Board Members of Conference Series LLC Journals as well as from neurologists, researchers and leaders from pharma, government organizations who made this conference as one of most successful and productive events in 2016 from Conference Series LLC.

The conference was carried out through various sessions, in which the discussions were held on the following scientific tracks:

· Central Nervous System Disorders

· Cognitive Neurology

· CNS and Neuro Surgery

· Cerebral Disorders

· Neuro Oncology and CNS

· Spinal Cord

· Neuronal Disorders

· Signal Transduction and CNS

· Genesis of Neurons

· Neuro Pharmaceutics

· Neurochemical Transmission

· Drug Metabolism in Drug Design

· Clinical aspects of CNS

· Case Study on CNS

· Clinical Trials on CNS

· CNS Biomarkers

· Perspective in Neuroscience and Neurology

The conference was initiated with a prominent keynote speaker, Dr. J B Strosznajder from Mossakowski Medical Research Centre, Polish Academy of Sciences, Poland. The above mentioned keynote speaker gave his energetic and fruitful contributions at CNS-2016.

All accepted abstracts have been indexed in Conferenceseries LLC Journal of Neurology & Neurophysiology as a special issue.

We are also obliged to various outside experts, company representatives and other eminent personalities who supported the conference by facilitating the discussion forums. Our sincere thanks to Organizing Committee Members for their gracious presence, support and assistance towards CNS 2016.

Past Reports Gallery

To Collaborate Scientific Professionals around the World

Conference Date September 17-18, 2018

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sponsor@conferenceseries.com

Speaker Opportunity

Poster Opportunity E-Poster Opportunity

Useful Links

Supported By

Journal of Neurological Disorders Journal of Neurology and Neuroscience Journal of Neurology & Neurophysiology

All accepted abstracts will be published in respective Conference Series International Journals.

Abstracts will be provided with Digital Object Identifier by

Nervous System and Nerve Diseases

August 17-18, 2018 Philadelphia, USA

Exploring Novelty and Vision On Nervous System and Nerve Disorders

Nervous System l Nervous System and Nervous Disorder conference| Neuropathy| Peripheral Neuropathy|Central Nervous System| Neuroscience| Neurology|Nervous System 2018| CME credits| Philadelphia | USA| Europe| Middle East| 2018

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