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PNS 2018

About Conference

PNS 2018 Organizing Committee, invites all the participants from all over the world to attend “International conference on Peripheral Nervous System Disorder” during May 23-24, 2018 at New York, USA. This gathering is predominantly will focus the most recent and energizing developments in each range of PNS research, and it will offer an exceptional opportunity for specialists from all over the world to meet, network, and distinguish with different scientific interactions.

Peripheral Nervous system is one of the main parts of Nervous system. It contains Ganglia and nerves outside the Brain and Spinal cord. Unlike Central nervous system, it is not protected by skull or column. And it is often exposed to toxins and mechanical injuries. It is divided into somatic Nervous system and Autonomic Nervous System. The main function of PNS is to connect CNS to limbs and other organs in the body. Peripheral Nervous System Disorder refers to the damage caused in the peripheral nerve that disrupts the passage of messages between CNS and PNS.

There are about more than 100 different kinds of Peripheral Nervous System Disorder. Approximately 20 million adults in USA are affected with diabetic Peripheral Neuropathy. About 86 million people with pre- diabetes are at risk of having Peripheral Neuropathy, from where 21.5 million were diagnosed with Peripheral Neuropathy. It is estimated that 20- 50% of HIV patients were suffering from Peripheral Neuropathy. 30% of cancer survivors were suffering from Chemotherapy induced Peripheral Neuropathy. The fact is that about half of the 42.5 million people don’t even know that they are affected with Peripheral Neuropathy.

Why to attend?

PNS 2018 will provide an opportunity to world researchers working in era of neurological disorders to deliver talk on their research. It will be a great opportunity to the speakers, experts, researchers from both academics and industrialist to discuss their research and views.

It is our greatest pleasure to welcome you to the “International conference on Peripheral Nervous System Disorder” (PNS 2018), May 23-24, 2018 at New York, USA.  The conference includes demonstration, symposium, workshops with different tracks in the field of neurological disorder. PNS 2018 is the leading gathering of neurologists, psychiatry, psychology researchers, and neurosurgeons with the theme of Research Strategies, propelled advancements and developments in Peripheral Neuropathy. Its main aim to deliver and exchange ideas with the leading scientists and to create awareness among people about Peripheral Neuropathy.

Target audience: Neurologists, Psychiatrists, Psychologists, Neurosurgeon, Head of the department, Director, Industries, Delegates, Clinical, Community members, Professors, Researchers, Students, Scientists, Nurses.

Ø  Neurologists and Directors

Ø  Physicians

Ø  Neuroscientists

Ø  Specialists

Ø  Researchers

Ø  Professors

Ø  Industrial Experts

Ø  Neurosurgeons

Ø  Psychiatrist

Ø  Nutritional Scientists

Ø  Lecturers and Students from Academia in the study of Parkinson disease

Ø  Students from Academia in the research of Neurology and Neuroscience

Ø  Therapists

 

Sessions/ Tracks

Session on Peripheral Nerve Disorder

Nervous system consists of two main parts namely Central Nervous System and Peripheral Nervous System. Peripheral Nervous system contains Ganglia and Nerves outside the Brain and spinal cord. PNS often exposed to toxins and mechanical injuries since it is not protected by skull or vertebral column. PNS is portioned into Somatic Nervous System and Autonomic Nervous System. The predominant function is to carry signals from Central Nervous System to all other organs of the body. There are about more than 100 different kinds of Peripheral Nerve Disorder. It refers to the damage occurs in the Peripheral Nerve that disrupts the passage of messages from CNS to PNS. The common symptoms are numbness, muscle weakness, Burning or tingling. 

Session on Peripheral Neuropathy

Peripheral neuropathy is one of the Nervous System Disorders. Depending on the nerves it may repair sensation, movement and organ functions. The main causes of this disorder are viral infection, vitamin deficiency, immune system diseases and medication like chemotherapy or antibiotics. Carpal tunnel syndrome is the most common Peripheral Neuropathy. There are many types of Nervous System Disorder according to the number of nerves affected, type of nerve affected and the process of nerve damage.

Session on Amyloid Neuropathy

The formation of amyloid fibrils or protein aggregation in the Autonomic Nervous system is termed as Amyloid Neuropathy. It is a rare group of Autosomal dominant disease. The aggregation of one precursor protein results in Peripheral Neuropathy or Autonomic Nervous System Dysfunction. The proteins include transthyretin, apolipoprotein A1and gelsolin. The treatment for Amyloid Neuropathy includes Liver Transplantation. As per European Medicine Agency, a drug called Tafamidis or Vyndaqel has proved to be effective in stabilizing transthyretin tetramer proteins. 

Session on Diabetic Neuropathy

Nerve damage that is associated with diabetes mellitus is referred to as Diabetic Neuropathy. This neuropathy affects all the Peripheral Nerves including motor Neurons, Autonomic Nervous system, sensory Neurons, pain neurons that eventually affects all organs and systems. The symptoms include numbness, Dysesthesia, Diarrhea, Dizziness, trouble with balance. The main factors for Diabetic Neuropathy are Microvascular disease, Advanced glycated end products, Polyol pathway, Sensorimotor polyneuropathy, Autonomic Neuropathy and Cranial neuropathy.

Session on Nerve Compression Syndrome

It is also referred to as Compression Neuropathy or Entrapment Neuropathy. It is a condition cause by direct pressure on a Nerve. The symptoms include pain, numbness, muscle weakness and tingling and the symptoms affects one part of the body. Compression Neuropathy can be caused due to prolonged compression on a particular Nerve or may be caused due to weight gain or peripheral edema. The treatment is based on the causes of Compression Neuropathy. Some compression Neuropathies are susceptible to surgery. Nerve induction studies are helpful in solving the diagnostic confusions.

Session on Brachial Plexus Neuropathy

Brachial Plexus is a connective Nerve that provides movements to shoulder, arm and hand which is in the neck region of the Spinal Cord. This nerve is composed of four cervical Nerve roots and the first thoracic nerve root. A birth Brachial Plexus injury is caused at the time delivery process. It was found to occur in 1.5 of every 1000 live births. Traumatic Brachial Plexus Injury is due to road accidents. Injuries are classified into four types namely Avulsion, Rupture, Neuroma, Neurapraxia. Surgery should be done to avulsion and rupture injuries. For Neuroma and Neuropraxia, the range of improvement varies. Many patients of Neuropraxia have gained 90-100% of their functions after the surgery.

Session on Hand-Arm Vibration Syndrome

The damages caused by vibration in fingers, hands and arms is known as Hand arm Vibration Syndrome. This syndrome is prevalent among people working with vibration tools and machineries. Vibration injuries are classified into: neurological disorders, vascular and musculoskeletal. Neurological vibration damage is irreversible causing complete impairment and disability. Vascular injuries damage the capillaries in the hands and fingers causing constriction of these capillaries in turn causes blanching(Whiteness) in the hands and fingers. Musculoskeletal injuries affect arthritis, tendonitis and bring changes in the muscle fibers. 

Session on Congenital insensitivity to pain

It is a medical condition which inhibits the ability to perceive physical pain. Since it affects the Peripheral Nervous system, it is considered as a form of Peripheral Neuropathy. People with this condition can feel difference between hot and cold or sharp and dull but they cannot sense. This leads to the accumulation of wounds, scares, health issues that may go unnoticed. It is genetic disorder that is inherited in an autosomal recessive pattern. Mutation in the gene SCN9A causes this condition.

Session on Guillain-Barre Syndrome

In this syndrome, body’s immune system attacks part of the Peripheral Nervous System. The cause and the treatment are unknown. It is extremely rare disorder that affects everyone irrespective of age and gender. It occurs a few days or week after the patient was diagnosed with respiratory or gastrointestinal viral infection. In Guillain-Barre Syndrome, the immune system damages the myelin sheath that surrounds the axon of the Peripheral Nervous System which eventually disrupts the signal between Central Nervous System and PNS. This results in the muscle weakness and tingling sensation in the leg.

Session on Neuralgia

Neuralgia is a severe pain due to damaged or irritated nerve. The causes are aging, multiple sclerosis, infection and diabetes. Neuralgia is classified into Trigeminal neuralgia, Glossopharyngeal neuralgia and Occipital neuralgia. It is diagnosed by identifying missing sensory and motor neurons with the help of Electromyography test. It is a rare disease where women are more affected than men. Treatments include medications like antidepressants and antiepileptics.

Session on Polyneuropathy

Polyneuropathy is a damage caused in the Peripheral Nervous System that results in numbness and burning sensation in the affected nerve. Diabetes and Guillain–Barré syndrome are disorders that may cause Polyneuropathy. It is divided into Distal axonopathy, Myelinopathy and Neuronopathy. The causes may be inherited or acquired. 

Session on Issacs Syndrome

Issacs Syndrome or Neuromyotonia is a form of Peripheral Nerve hyperexcitability which causes muscle stiffness, continuous contracting or twitching muscles and diminished reflexes. It is a rare Neuromuscular disorder which affects people between 15 and 60. The cause may be hereditary or acquired. There are three types of this syndrome namely Chronic, Monophasic and Relapsing Remitting. There is no cure for Issacs Syndrome but the condition is treatable with anticonvulsants and plasma exchange.

Session on Tarlov Cyst

Tarlov Cysts are the dilation of the nerve root sheaths and are abnormal sac filled with cerebrospinal fluid that results in progressively painful nerve. It is also termed as perineural or sacral nerve root cysts. They are associated in patient with connective tissue disorders. They are often located at the S2 and S3 levels of sacrum which is base of the spinal cord. Transcutaneous Electrical Nerve Stimulation has been considered as a treatment for pain management.

Session on Complex Regional Pain Syndromes

It is a chronic pain condition often affects one limb after an injury. It occurs due to damage caused to peripheral nervous system or central nervous system. It is classified into CRPS- I and CRPS- II. The main symptom includes prolonged pain in the affected limb. Trauma or injury is the main cause for CRPS. It is more common in women at the age of 40. The treatments include Rehabilitation and physical therapy, Psychotherapy and medications.

Session on Mononeuropathies

The damage to a single Peripheral Nerve is known as Mononeuropathy. Physical injury is the main risk factor for Mononeuropathy. The nerve injury results from accidents, prolonged exposure to cold or heat, radiation therapy for cancer, infections such as leprosy or Lyme disease and repeated injuries. Abnormal or loss of sensation and pain occurs in the affected nerve.

Session on Acrodynia

It is a disorder that primarily affects children due to chronic exposure to mercury. It results in Peripheral Neuropathies, irritability, pink coloration in hands and feet and photophobia. Dental amalgam used for filling is suspected to be the source of mercury toxicity. Chelating agents are used to prevent methylmercury uptake by erythrocytes and liver cells.  

Session on Neurofibromatosis

It is an autosomal dominant disorder that causes tumors in the nervous system. Their types are neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis. Even though the symptoms are mild, the complications of neurofibromatosis can be severe. It results in hearing loss, loss of vision, Heart problems and severe pain. 

Session on Neuritis

This term is used to describe a group of diseases involving the inflammation of a nerve or a group of nerves. Neuritis along with other diseases affecting Peripheral Nerves are called Neuropathies. It is characterized by changes in sensation, weakness, pain and muscle wasting. Injuries, Nutritional Deficiencies, Infections and toxins are the main causes of Neuritis. Several diseases lead to neuritis namely Diabetes mellitus, Hypothyroidism, Porphyria.

Session on Neuroplasticity

The ability of the Brain to alter at any age is referred to as Neuroplasticity or Brain Plasticity. The recent neuroscience research proves that Neuroplasticity is the basis for brain training exercises which revolutionized the brain health and science research. There is a great reception for Brain plasticity based therapies for many cognitive problems since it is a non- invasive treatment.

Session on Neuroregenaration

Regrowth of Nervous tissues and cells including Neurons, glia, axons, myelin or synapses is known as Neuroregenaration. On site of the injury in Peripheral Nervous System, the migration of phagocytes, Schwann cells and macrophages will be elicited to clear away the damages tissues. The regrowth of Axons can occur after injury. Neuroregenaration in Peripheral Nervous System happens to a certain degree. 

Session on Diagnosis of Peripheral Nervous Disorder

Identification of Peripheral Nerve disorder can be done in my ways. Mainly Nerve Conduction tests and Electromyography(EMG). Other tests include Autonomic testing, Cerebrospinal Fluid Analysis and Nerve Biopsy Analysis. The attention must be given to the types of nerves affected and the pattern of involvement. Diabetes is one of the main causes of Peripheral Nervous Disorder. Eventually Diabetes people have high risk for Peripheral Nerve injury

Session on Therapeutics of Peripheral Nerve Disorder

Treatment for the Peripheral Nerve Disorder is based on the causes of disorder. Pain medications can be given to the patients for controlling moderate pain. Another potential therapy is Transcutaneous electronic nerve stimulation (TENS). This treatment helps in disrupting nerves from transmitting pain signals to the brain. Ergonomic casts or splints helps in relieving pain.  Demyelinating Neurotherapies is fast growing technique to treat Peripheral Nerve Disorder.

Session on Imaging of Peripheral Nerve

The tools used for imaging Peripheral Nerve are Positron Emission Tomography(PET), Diffusion Tensor imaging(DTI), Magnetic Resonance Neurography(MRN), Computerized Tomography(CT), Plain X- Ray. MRN is the advanced technique used to image Peripheral Nerve for the diagnosis of any disorder in the Nerves and Neuromuscular diseases. It can image any Nerves in the body and are commonly used for the diagnosis of Nerve disorder in Brachial Plexus. 

 

 

 

Market Analysis

ThemeExploring Novelty and Vision on Peripheral Nervous System

On behalf of the Conference Organizing Committee, it is our heartiest welcome you to the " International Conference on Peripheral Nervous System" during May 23-242018 in New York, USA.

Importance and Scope:

Peripheral Nervous system disorder mainly causes due to damage occurred to peripheral nerves resulting in weakness, numbness, and usually in hands and feet. Peripheral neuropathy is caused due to traumatic injuries, infections, metabolic problems, inherited causes and exposure to toxins, and most commonly by diabetes mellitus.

Geriatric and obese population is growing at a rapid pace across the world and these people are at high risk for developing peripheral neuropathy. Centers for Disease Control and Prevention stated, that people who are diagnosed with diabetes mostly obese. Thus, with rising geriatric population and growing prevalence of diabetes propels the global market demand of peripheral neuropathy treatment. The U.S. Census Bureau stated that, the fastest growing segment of the U.S. population is geriatric group. According to World Health Organization (WHO) estimates, the global geriatric population would increase from 524 million in 2010 to around 2 billion by 2050. Moreover, the global geriatric population would grow at the fastest rate in developed countries such as the U.S., the U.K. and Japan. World Health Organization (WHO) stated in 2012 that, more than 40 million children under the age of 5 were overweight or obese. Moreover, it has also estimated that 10% of the world adult population was obese in the year 2012.

According to the latest market report the global peripheral neuropathy market was valued at US$ 1,470.9 million in 2016, and is expected to reach US$ 1,998.8 million by 2025, expanding at the rate of 3.2% from 2017 to 2025.

In the base 2016, North America was observed as the largest market for peripheral neuropathy. The rising geriatric population, growing incidences of diabetes in the region is the prime factor driving the North America peripheral neuropathy market. Asia Pacific is anticipated to be fastest growing market for the forecast period 2017-2025.

 

Conference Highlights

Peripheral Nerve Disorder

Peripheral Neuropathy

Amyloid Neuropathy

Brachial Plexus Neuropathy

Diabetic Neuropathy

Nerve Compression Syndrome

Hand-Arm Vibration Syndrome

Congenital insensitivity to pain

Guillain-Barre Syndrome

Neuralgia

Polyneuropathy

Issacs Syndrome

Tarlov Cyst

Complex Regional Pain Syndromes

Mononeuropathy

Acrodynia

Neurofibromatosis

Neuritis

Neuroplasticity

Neuroregenaration

Diagnosis of Peripheral Nervous Disorder

Therapeutics of Peripheral Nerve Disorder

 

Major Centers for Peripheral Neuropathy around the world

The Foundation for Peripheral Neuropathy

UCSF Medical Center

The Center for Peripheral Neuropathy

Emory Healthcare

Ohio State Neuromuscular Disorders

American Brain Foundation`

NYU Langone Medical Center

The National Organization for Rare Disorders (NORD)

Past Conference Report

CNS 2016

Central Nervous System 2016- Reports

The 2nd International Conference on Central Nervous System Disorders and Therapeutics hosted by the Conference Series LLC was held on December 05-07, 2016 at JW Marriott Hotel, Dubai, UAE. Generous response and active participation was received from the Editorial Board Members of Conference Series LLC Journals as well as from neurologists, researchers and leaders from pharma, government organizations who made this conference as one of most successful and productive events in 2016 from Conference Series LLC.

The conference was carried out through various sessions, in which the discussions were held on the following scientific tracks:

·         Central Nervous System Disorders

·         Cognitive Neurology

·         CNS and Neuro Surgery

·         Cerebral Disorders

·         Neuro Oncology and CNS

·         Spinal Cord

·         Neuronal Disorders

·         Signal Transduction and CNS

·         Genesis of Neurons

·         Neuro Pharmaceutics

·         Neurochemical Transmission

·         Drug Metabolism in Drug Design

·         Clinical aspects of CNS

·         Case Study on CNS

·         Clinical Trials on CNS

·         CNS Biomarkers

·         Perspective in Neuroscience and Neurology

The conference was initiated with a prominent keynote speaker, Dr. J B Strosznajder from Mossakowski Medical Research Centre, Polish Academy of Sciences, Poland. The above mentioned keynote speaker gave his energetic and fruitful contributions at CNS-2016.

All accepted abstracts have been indexed in Conferenceseries LLC Journal of Neurology & Neurophysiology as a special issue.

We are also obliged to various outside experts, company representatives and other eminent personalities who supported the conference by facilitating the discussion forums. Our sincere thanks to Organizing Committee Members for their gracious presence, support and assistance towards CNS 2016.


Past Reports  Proceedings  Gallery  

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All accepted abstracts will be published in respective Conferenceseries International Journals.

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